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Publications

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2022

  • Sack, I. Magnetic resonance elastography from fundamental soft-tissue mechanics to diagnostic imaging. Nat Rev Phys (2022). doi: 10.1038/s42254-022-00543-2.
  • Elsholtz FHJ, Reiter R, Marticorena Garcia SR, Braun J, Sack I, Hamm B, Schaafs LA. Multifrequency magnetic resonance elastography-based tomoelastography of the parotid glands-feasibility and reference values. Dentomaxillofac Radiol. 2022 Jan 1;51(1):20210337. doi: 10.1259/dmfr.20210337 . Epub 2021 Sep 24. PMID: 34558305; PMCID: PMC8693321.
  • Szekeres GP, Pagel K, Heiner Z. Analytical challenges of glycosaminoglycans at biological interfaces. Anal Bioanal Chem. 2022 Jan;414(1):85-93. doi: 10.1007/s00216-021-03705-w . Epub 2021 Oct 14. PMID: 34647134; PMCID: PMC8514262.

2021

  • Karlsson R, Chopra P, Joshi A, Yang Z, Vakhrushev SY, Clausen TM, Painter CD, Szekeres GP, Chen YH, Sandoval DR, Hansen L, Esko JD, Pagel K, Dyer DP, Turnbull JE, Clausen H, Boons GJ, Miller RL. Dissecting structure-function of 3-O-sulfated heparin and engineered heparan sulfates. Sci Adv. 2021 Dec 24;7(52):eabl6026. doi: 10.1126/sciadv.abl6026. Epub 2021 Dec 22. PMID: 34936441; PMCID: PMC8694587.
  • Golusda L, Kühl AA, Siegmund B, Paclik D. Reducing Pain in Experimental Models of Intestinal Inflammation Affects the Immune Response. Inflamm Bowel Dis. 2021 Dec 6:izab290. doi: 10.1093/ibd/izab290. Epub ahead of print. PMID: 34871378.
  • Kader A, Brangsch J, Reimann C, Kaufmann JO, Mangarova DB, Moeckel J, Adams LC, Zhao J, Saatz J, Traub H, Buchholz R, Karst U, Hamm B, Makowski MR. Visualization and Quantification of the Extracellular Matrix in Prostate Cancer Using an Elastin Specific Molecular Probe. Biology (Basel). 2021 Nov 22;10(11):1217. doi: 10.3390/biology10111217. PMID: 34827210; PMCID: PMC8615039.
  • Mangarova DB, Bertalan G, Jordan J, Brangsch J, Kader A, Möckel J, Adams LC, Sack I, Taupitz M, Hamm B, Braun J, Makowski MR. Microscopic multifrequency magnetic resonance elastography of ex vivo abdominal aortic aneurysms for extracellular matrix imaging in a mouse model. Acta Biomater. 2021 Nov 21:S1742-7061(21)00774-1. doi: 10.1016/j.actbio.2021.11.026. Epub ahead of print. PMID: 34818577.
  • Jordan JEL, Bertalan G, Meyer T, Tzschätzsch H, Gauert A, Bramè L, Herthum H, Safraou Y, Schröder L, Braun J, Hagemann AIH, Sack I. Microscopic multifrequency MR elastography for mapping viscoelasticity in zebrafish. Magn Reson Med. 2021 Nov 9. doi: 10.1002/mrm.29066. Epub ahead of print. PMID: 34752638.
  • Werner P, Taupitz M, Schröder L, Schuenke P. An NMR relaxometry approach for quantitative investigation of the transchelation of gadolinium ions from GBCAs to a competing macromolecular chelator. Sci Rep. 2021 Nov 5;11(1):21731. doi: 10.1038/s41598-021-00974-4. PMID: 34741037; PMCID: PMC8571392.
  • Zasłona ME, Downey AM, Seeberger PH, Moscovitz O. Semi- and fully synthetic carbohydrate vaccines against pathogenic bacteria: recent developments. Biochem Soc Trans. 2021 Nov 1;49(5):2411-2429. doi: 10.1042/BST20210766. PMID: 34495299; PMCID: PMC8589429.
  • Lilaj L, Herthum H, Meyer T, Shahryari M, Bertalan G, Caiazzo A, Braun J, Fischer T, Hirsch S, Sack I. Inversion-recovery MR elastography of the human brain for improved stiffness quantification near fluid-solid boundaries. Magn Reson Med. 2021 Nov;86(5):2552-2561. doi: 10.1002/mrm.28898. Epub 2021 Jun 28. PMID: 34184306.
  • Gültekin E, Wetz C, Braun J, Geisel D, Furth C, Hamm B, Sack I, Marticorena Garcia SR. Added Value of Tomoelastography for Characterization of Pancreatic Neuroendocrine Tumor Aggressiveness Based on Stiffness. Cancers (Basel). 2021 Oct 15;13(20):5185. doi: 10.3390/cancers13205185. PMID: 34680334; PMCID: PMC8533708.
  • Golusda L, Kühl AA, Siegmund B, Paclik D. Extracellular Matrix Components as Diagnostic Tools in Inflammatory Bowel Disease. Biology (Basel). 2021 Oct 11;10(10):1024. doi: 10.3390/biology10101024. PMID: 34681123; PMCID: PMC8533508.
  • Zappe A, Miller RL, Struwe WB, Pagel K. State-of-the-art glycosaminoglycan characterization. Mass Spectrom Rev. 2021 Oct 5. doi: 10.1002/mas.21737. Epub ahead of print. PMID: 34608657.
  • Haeckel A, Ascher L, Beindorff N, Prasad S, Garczyńska K, Guo J, Schellenberger E. Long-circulating XTEN864-annexin A5 fusion protein for phosphatidylserine-related therapeutic applications. Apoptosis. 2021 Oct;26(9-10):534-547. doi: 10.1007/s10495-021-01686-w. Epub 2021 Aug 17. PMID: 34405304; PMCID: PMC8370750.
  • Baki A, Wiekhorst F, Bleul R. Advances in Magnetic Nanoparticles Engineering for Biomedical Applications-A Review. Bioengineering (Basel). 2021 Sep 30;8(10):134. doi: 10.3390/bioengineering8100134. PMID: 34677207; PMCID: PMC8533261.
  • Möckel J, Brangsch J, Reimann C, Kaufmann JO, Sack I, Mangarova DB, Kader A, Taupitz M, Adams LC, Keller S, Ludwig A, Hamm B, Botnar RM, Makowski MR. Assessment of Albumin ECM Accumulation and Inflammation as Novel In Vivo Diagnostic Targets for Multi-Target MR Imaging. Biology (Basel). 2021 Sep 27;10(10):964. doi: 10.3390/biology10100964. PMID: 34681063; PMCID: PMC8533611.
  • Grabarics M, Lettow M, Kirschbaum C, Greis K, Manz C, Pagel K. Mass Spectrometry-Based Techniques to Elucidate the Sugar Code. Chem Rev. 2021 Sep 7. doi: 10.1021/acs.chemrev.1c00380. Epub ahead of print. PMID: 34491038.
  • Collettini F, Brangsch J, Reimann C, Chapiro J, Savic LJ, Buchholz R, Keller S, Hamm B, Goldberg SN, Makowski MR. Hepatic Radiofrequency Ablation: Monitoring of Ablation-Induced Macrophage Recruitment in the Periablational Rim Using SPION-Enhanced Macrophage-Specific Magnetic Resonance Imaging. Invest Radiol. 2021 Sep 1;56(9):591-598. doi: 10.1097/RLI.0000000000000777. PMID: 33787536.
  • Reiter R, Shahryari M, Tzschätzsch H, Haas M, Bayerl C, Siegmund B, Hamm B, Asbach P, Braun J, Sack I. Influence of fibrosis progression on the viscous properties of in vivo liver tissue elucidated by shear wave dispersion in multifrequency MR elastography. J Mech Behav Biomed Mater. 2021 Sep;121:104645. doi: 10.1016/j.jmbbm.2021.104645. Epub 2021 Jun 18. PMID: 34166871.
  • Silva RV, Morr AS, Mueller S, Koch SP, Boehm-Sturm P, Rodriguez-Sillke Y, Kunkel D, Tzschätzsch H, Kühl AA, Schnorr J, Taupitz M, Sack I, Infante-Duarte C. Contribution of Tissue Inflammation and Blood-Brain Barrier Disruption to Brain Softening in a Mouse Model of Multiple Sclerosis. Front Neurosci. 2021 Aug 23;15:701308. doi: 10.3389/fnins.2021.701308. PMID: 34497486; PMCID: PMC8419310.
  • Hu J, Guo J, Pei Y, Hu P, Li M, Sack I, Li W. Rectal Tumor Stiffness Quantified by In VivoTomoelastography and Collagen Content Estimated by Histopathology Predict Tumor Aggressiveness. Front Oncol. 2021 Aug 13;11:701336. doi: 10.3389/fonc.2021.701336. PMID: 34485136; PMCID: PMC8415020.
  • Garczyńska K, Tzschätzsch H, Assili S, Kühl AA, Häckel A, Schellenberger E, Berndt N, Holzhütter HG, Braun J, Sack I, Guo J. Effect of Post-mortem Interval and Perfusion on the Biophysical Properties of ex vivo Liver Tissue Investigated Longitudinally by MRE and DWI. Front Physiol. 2021 Aug 3;12:696304. doi: 10.3389/fphys.2021.696304. PMID: 34413787; PMCID: PMC8369239.
  • Atreya R, Siegmund B. Location is important: differentiation between ileal and colonic Crohn's disease. Nat Rev Gastroenterol Hepatol. 2021 Aug;18(8):544-558. doi: 10.1038/s41575-021-00424-6. Epub 2021 Mar 12. PMID: 33712743.
  • Reiter R, Loch FN, Kamphues C, Bayerl C, Marticorena Garcia SR, Siegmund B, Kühl AA, Hamm B, Braun J, Sack I, Asbach P. Feasibility of Intestinal MR Elastography in Inflammatory Bowel Disease. J Magn Reson Imaging. 2021 Jul 12. doi: 10.1002/jmri.27833. Epub ahead of print. PMID: 34254389.
  • Biskup K, Stellmach C, Braicu EI, Sehouli J, Blanchard V. Chondroitin Sulfate Disaccharides, a Serum Marker for Primary Serous Epithelial Ovarian Cancer. Diagnostics (Basel). 2021 Jun 23;11(7):1143. doi: 10.3390/diagnostics11071143. PMID: 34201657; PMCID: PMC8304809.
  • Szekeres GP, Krekic S, Miller RL, Mero M, Pagel K, Heiner Z. The interaction of chondroitin sulfate with a lipid monolayer observed by using nonlinear vibrational spectroscopy. Phys Chem Chem Phys. 2021 Jun 16;23(23):13389-13395. doi: 10.1039/d1cp01975a. PMID: 34105546; PMCID: PMC8207512.
  • Kratz H, Mohtashamdolatshahi A, Eberbeck D, Kosch O, Wiekhorst F, Taupitz M, Hamm B, Stolzenburg N, Schnorr J. Tailored Magnetic Multicore Nanoparticles for Use as Blood Pool MPI Tracers. Nanomaterials (Basel). 2021 Jun 10;11(6):1532. doi: 10.3390/nano11061532. PMID: 34200588; PMCID: PMC8228684.
  • Baki A, Remmo A, Löwa N, Wiekhorst F, Bleul R. Albumin-Coated Single-Core Iron Oxide Nanoparticles for Enhanced Molecular Magnetic Imaging (MRI/MPI). Int J Mol Sci. 2021 Jun 9;22(12):6235. doi: 10.3390/ijms22126235. PMID: 34207769; PMCID: PMC8229057.
  • Freise C, Querfeld U, Ludwig A, Hamm B, Schnorr J, Taupitz M. Uraemic extracellular vesicles augment osteogenic transdifferentiation of vascular smooth muscle cells via enhanced AKT signalling and PiT-1 expression. J Cell Mol Med. 2021 Jun;25(12):5602-5614. doi: 10.1111/jcmm.16572. Epub 2021 May 7. PMID: 33960650; PMCID: PMC8184672.
  • Xie J, Haeckel A, Hauptmann R, Ray IP, Limberg C, Kulak N, Hamm B, Schellenberger E. Iron(III)-tCDTA derivatives as MRI contrast agents: Increased T1 relaxivities at higher magnetic field strength and pH sensing. Magn Reson Med. 2021 Jun;85(6):3370-3382. doi: 10.1002/mrm.28664. Epub 2021 Feb 4. PMID: 33538352.
  • Uca YO, Hallmann D, Hesse B, Seim C, Stolzenburg N, Pietsch H, Schnorr J, Taupitz M. Microdistribution of Magnetic Resonance Imaging Contrast Agents in Atherosclerotic Plaques Determined by LA-ICP-MS and SR-μXRF Imaging. Mol Imaging Biol. 2021 Jun;23(3):382-393. doi: 10.1007/s11307-020-01563-z. Epub 2020 Dec 7. PMID: 33289060; PMCID: PMC8099766.
  • Aldoj N, Biavati F, Dewey M, Hennemuth A, Asbach P, Sack I. Fully automated quantification of in vivo viscoelasticity of prostate zones using magnetic resonance elastography with Dense U-net segmentation. arXiv preprint arXiv: 210611284. June 2021.
  • Lettow M, Greis K, Grabarics M, Horlebein J, Miller RL, Meijer G, von Helden G, Pagel K. Chondroitin Sulfate Disaccharides in the Gas Phase: Differentiation and Conformational Constraints. J Phys Chem A. 2021 May 27;125(20):4373-4379. doi: 10.1021/acs.jpca.1c02463. Epub 2021 May 12. PMID: 33979516; PMCID: PMC8279649.
  • Reiter R, Shahryari M, Tzschätzsch H, Klatt D, Siegmund B, Hamm B, Braun J, Sack I, Asbach P. Spatial heterogeneity of hepatic fibrosis in primary sclerosing cholangitis vs. viral hepatitis assessed by MR elastography. Sci Rep. 2021 May 10;11(1):9820. doi: 10.1038/s41598-021-89372-4. PMID: 33972639; PMCID: PMC8110576.
  • Herthum H, Shahryari M, Tzschätzsch H, Schrank F, Warmuth C, Görner S, Hetzer S, Neubauer H, Pfeuffer J, Braun J, Sack I. Real-Time Multifrequency MR Elastography of the Human Brain Reveals Rapid Changes in Viscoelasticity in Response to the Valsalva Maneuver. Front Bioeng Biotechnol. 2021 May 5;9:666456. doi: 10.3389/fbioe.2021.666456. PMID: 34026743; PMCID: PMC8131519.
  • Twamley SG, Stach A, Heilmann H, Söhl-Kielczynski B, Stangl V, Ludwig A, Münster-Wandowski A. Immuno-Electron and Confocal Laser Scanning Microscopy of the Glycocalyx. Biology (Basel). 2021 May 4;10(5):402. doi: 10.3390/biology10050402. PMID: 34064459; PMCID: PMC8147923.
  • Li M, Guo J, Hu P, Jiang H, Chen J, Hu J, Asbach P, Sack I, Li W. Tomoelastography Based on Multifrequency MR Elastography for Prostate Cancer Detection: Comparison with Multiparametric MRI. Radiology. 2021 May;299(2):362-370. doi: 10.1148/radiol.2021201852. Epub 2021 Mar 9. Erratum in: Radiology. 2021 May;299(2):E259. PMID: 33687285.
  • Zhu L, Guo J, Jin Z, Xue H, Dai M, Zhang W, Sun Z, Xu J, Marticorena Garcia SR, Asbach P, Hamm B, Sack I. Distinguishing pancreatic cancer and autoimmune pancreatitis with in vivo tomoelastography. Eur Radiol. 2021 May;31(5):3366-3374. doi: 10.1007/s00330-020-07420-5. Epub 2020 Oct 30. PMID: 33125553.
  • Adams LC, Brangsch J, Kaufmann JO, Mangarova DB, Moeckel J, Kader A, Buchholz R, Karst U, Botnar RM, Hamm B, Makowski MR, Keller S. Effect of Doxycycline on Survival in Abdominal Aortic Aneurysms in a Mouse Model. Contrast Media Mol Imaging. 2021 Apr 27;2021:9999847. doi: 10.1155/2021/9999847. PMID: 34007253; PMCID: PMC8099506.
  • Maschmeyer P, Zimmermann J, Kühl AA. Murine T-Cell Transfer Colitis as a Model for Inflammatory Bowel Disease. Methods Mol Biol. 2021;2285:349-373. doi: 10.1007/978-1-0716-1311-5_26. PMID: 33928564.
  • Shahryari M, Meyer T, Warmuth C, Herthum H, Bertalan G, Tzschätzsch H, Stencel L, Lukas S, Lilaj L, Braun J, Sack I. Reduction of breathing artifacts in multifrequency magnetic resonance elastography of the abdomen. Magn Reson Med. 2021 Apr;85(4):1962-1973. doi: 10.1002/mrm.28558. Epub 2020 Oct 26. PMID: 33104294.
  • Collettini F, Reimann C, Brangsch J, Chapiro J, Savic LJ, Onthank DC, Robinson SP, Karst U, Buchholz R, Keller S, Hamm B, Goldberg SN, Makowski MR. Elastin-specific MRI of extracellular matrix-remodelling following hepatic radiofrequency-ablation in a VX2 liver tumor model. Sci Rep. 2021 Mar 25;11(1):6814. doi: 10.1038/s41598-021-86417-6. PMID: 33767303; PMCID: PMC7994448.
  • Hudert CA, Tzschätzsch H, Rudolph B, Loddenkemper C, Holzhütter HG, Kalveram L, Wiegand S, Braun J, Sack I, Guo J. How histopathologic changes in pediatric nonalcoholic fatty liver disease influence in vivo liver stiffness. Acta Biomater. 2021 Mar 15;123:178-186. doi: 10.1016/j.actbio.2021.01.019. Epub 2021 Jan 17. PMID: 33472102.
  • Adams L, Brangsch J, Hamm B, Makowski MR, Keller S. Targeting the Extracellular Matrix in Abdominal Aortic Aneurysms Using Molecular Imaging Insights. Int J Mol Sci. 2021 Mar 7;22(5):2685. doi: 10.3390/ijms22052685. PMID: 33799971; PMCID: PMC7962044.
  • Lilaj L, Fischer T, Guo J, Braun J, Sack I, Hirsch S. Separation of fluid and solid shear wave fields and quantification of coupling density by magnetic resonance poroelastography. Magn Reson Med. 2021 Mar;85(3):1655-1668. doi: 10.1002/mrm.28507. Epub 2020 Sep 9. PMID: 32902011.
  • Marticorena Garcia SR, Althoff CE, Dürr M, Halleck F, Budde K, Grittner U, Burkhardt C, Jöhrens K, Braun J, Fischer T, Hamm B, Sack I, Guo J. Tomoelastography for Longitudinal Monitoring of Viscoelasticity Changes in the Liver and in Renal Allografts after Direct-Acting Antiviral Treatment in 15 Kidney Transplant Recipients with Chronic HCV Infection. J Clin Med. 2021 Feb 1;10(3):510. doi: 10.3390/jcm10030510. PMID: 33535495; PMCID: PMC7867050.
  • Herthum H, Dempsey SCH, Samani A, Schrank F, Shahryari M, Warmuth C, Tzschätzsch H, Braun J, Sack I. Superviscous properties of the in vivo brain at large scales. Acta Biomater. 2021 Feb;121:393-404. doi: 10.1016/j.actbio.2020.12.027. Epub 2020 Dec 14. PMID: 33326885.
  • Löwa N, Meier F, Welz R, Kratz H, Paysen H, Schnorr J, Taupitz M, Klein T, Wiekhorst F. Novel platform for the multidimensional analysis of magnetic nanoparticles. Journal of Magnetism and Magnetic Materials. 2021; 518: 167443. doi: 10.1016/j.jmmm.2020.167443.
  • Hildebrand S, Löwa N, Paysen H, Fratila RM, Reverte-Salisa L, Trakoolwilaiwan T, Niu Z, Kasparis G, Preuss SF, Kosch O, M de la Fuente J, Thanh NTK, Wiekhorst F, Pfeifer A. Quantification of Lipoprotein Uptake in VivoUsing Magnetic Particle Imaging and Spectroscopy. ACS Nano. 2021 Jan 26;15(1):434-446. doi: 10.1021/acsnano.0c03229. Epub 2020 Dec 11. PMID: 33306343.

2020

  • Hetzer S, Hirsch S, Braun J, Sack I, Weygandt M. Viscoelasticity of striatal brain areas reflects variations in body mass index of lean to overweight male adults. Brain Imaging Behav. 2020 Dec;14(6):2477-2487. doi: 10.1007/s11682-019-00200-w. PMID: 31512097.
  • Dehlinger A, Seim C, Stiel H, Twamley S, Ludwig A, Kördel M, Grötzsch D, Rehbein S, Kanngießer B. Laboratory Soft X-Ray Microscopy with an Integrated Visible-Light Microscope-Correlative Workflow for Faster 3D Cell Imaging. Microsc Microanal. 2020 Dec;26(6):1124-1132. doi: 10.1017/S1431927620024447. PMID: 33023699.
  • Marticorena Garcia SR, Zhu L, Gültekin E, Schmuck R, Burkhardt C, Bahra M, Geisel D, Shahryari M, Braun J, Hamm B, Jin ZY, Sack I, Guo J. Tomoelastography for Measurement of Tumor Volume Related to Tissue Stiffness in Pancreatic Ductal Adenocarcinomas. Invest Radiol. 2020 Dec;55(12):769-774. doi: 10.1097/RLI.0000000000000704. PMID: 32796197.
  • Keller S, Borde T, Brangsch J, Reimann C, Kader A, Schulze D, Buchholz R, Kaufmann JO, Karst U, Schellenberger E, Hamm B, Makowski MR. Assessment of the hepatic tumor extracellular matrix using elastin-specific molecular magnetic resonance imaging in an experimental rabbit cancer model. Sci Rep. 2020 Nov 27;10(1):20785. doi: 10.1038/s41598-020-77624-8. PMID: 33247185; PMCID: PMC7695832.
  • Paysen H, Kosch O, Wells J, Loewa N, Wiekhorst F. Characterization of noise and background signals in a magnetic particle imaging system. Phys Med Biol. 2020 Nov 27;65(23). doi: 10.1088/1361-6560/abc364. PMID: 33086200.
  • Garczyńska K, Tzschätzsch H, Kühl AA, Morr AS, Lilaj L, Häckel A, Schellenberger E, Berndt N, Holzhütter HG, Braun J, Sack I, Guo J. Changes in Liver Mechanical Properties and Water Diffusivity During Normal Pregnancy Are Driven by Cellular Hypertrophy. Front Physiol. 2020 Nov 23;11:605205. doi: 10.3389/fphys.2020.605205. PMID: 33329058; PMCID: PMC7719759.
  • Löwa N, Gutkelch D, Welge EA, Welz R, Meier F, Baki A, Bleul R, Klein T, Wiekhorst F. Novel Benchtop Magnetic Particle Spectrometer for Process Monitoring of Magnetic Nanoparticle Synthesis. Nanomaterials (Basel). 2020 Nov 17;10(11):2277. doi: 10.3390/nano10112277. PMID: 33213004; PMCID: PMC7698567.
  • Brangsch J, Reimann C, Kaufmann JO, Adams LC, Onthank D, Thöne-Reineke C, Robinson S, Wilke M, Weller M, Buchholz R, Karst U, Botnar R, Hamm B, Makowski MR. Molecular MR-Imaging for Noninvasive Quantification of the Anti-Inflammatory Effect of Targeting Interleukin-1β in a Mouse Model of Aortic Aneurysm. Mol Imaging. 2020 Jan-Dec;19:1536012120961875. doi: 10.1177/1536012120961875. PMID: 33216687; PMCID: PMC7682246.
  • Mohtashamdolatshahi A, Kratz H, Kosch O, Hauptmann R, Stolzenburg N, Wiekhorst F, Sack I, Hamm B, Taupitz M, Schnorr J. In vivo magnetic particle imaging: angiography of inferior vena cava and aorta in rats using newly developed multicore particles. Sci Rep. 2020 Oct 14;10(1):17247. doi: 10.1038/s41598-020-74151-4. PMID: 33057029; PMCID: PMC7560824.
  • Klein O, Haeckel A, Reimer U, Nebrich G, Schellenberger E. Multiplex enzyme activity imaging by MALDI-IMS of substrate library conversions. Sci Rep. 2020 Sep 23;10(1):15522. doi: 10.1038/s41598-020-72436-2. PMID: 32968143; PMCID: PMC7511933.
  • Wells J , Twamley S , Sekar A , Ludwig A , Paysen H , Kosch O , Wiekhorst F . Lissajous scanning magnetic particle imaging as a multifunctional platform for magnetic hyperthermia therapy. Nanoscale. 2020 Sep 21;12(35):18342-18355. doi: 10.1039/d0nr00604a. Epub 2020 Sep 1. PMID: 32869808.
  • Adams LC, Brangsch J, Reimann C, Kaufmann JO, Buchholz R, Karst U, Botnar RM, Hamm B, Makowski MR. Simultaneous molecular MRI of extracellular matrix collagen and inflammatory activity to predict abdominal aortic aneurysm rupture. Sci Rep. 2020 Sep 16;10(1):15206. doi: 10.1038/s41598-020-71817-x. Erratum in: Sci Rep. 2021 May 4;11(1):9860. PMID: 32939002; PMCID: PMC7494914.
  • Baki A, Löwa N, Remmo A, Wiekhorst F, Bleul R. Micromixer Synthesis Platform for a Tuneable Production of Magnetic Single-Core Iron Oxide Nanoparticles. Nanomaterials (Basel). 2020 Sep 15;10(9):1845. doi: 10.3390/nano10091845. PMID: 32942715; PMCID: PMC7560047.
  • Keller S, Chapiro J, Brangsch J, Reimann C, Collettini F, Sack I, Savic LJ, Hamm B, Goldberg SN, Makowski M. Quantitative MRI for Assessment of Treatment Outcomes in a Rabbit VX2 Hepatic Tumor Model. J Magn Reson Imaging. 2020 Sep;52(3):668-685. doi: 10.1002/jmri.26968. Epub 2019 Nov 12. PMID: 31713973.
  • Lettow M, Grabarics M, Greis K, Mucha E, Thomas DA, Chopra P, Boons GJ, Karlsson R, Turnbull JE, Meijer G, Miller RL, von Helden G, Pagel K. Cryogenic Infrared Spectroscopy Reveals Structural Modularity in the Vibrational Fingerprints of Heparan Sulfate Diastereomers. Anal Chem. 2020 Aug 4;92(15):10228-10232. doi: 10.1021/acs.analchem.0c02048. Epub 2020 Jul 21. PMID: 32658472.
  • Siegmund B. Janus Kinase inhibitors in the New Treatment Paradigms of Inflammatory Bowel Disease. J Crohns Colitis. 2020 Aug 1;14(Supplement_2):S761-S766. doi: 10.1093/ecco-jcc/jjaa003. PMID: 31922534; PMCID: PMC7395309.
  • Asbach P, Ro SR, Aldoj N, Snellings J, Reiter R, Lenk J, Köhlitz T, Haas M, Guo J, Hamm B, Braun J, Sack I. In Vivo Quantification of Water Diffusion, Stiffness, and Tissue Fluidity in Benign Prostatic Hyperplasia and Prostate Cancer. Invest Radiol. 2020 Aug;55(8):524-530. doi: 10.1097/RLI.0000000000000685. PMID: 32496317.
  • Mangarova DB, Brangsch J, Mohtashamdolatshahi A, Kosch O, Paysen H, Wiekhorst F, Klopfleisch R, Buchholz R, Karst U, Taupitz M, Schnorr J, Hamm B, Makowski MR. Ex vivo magnetic particle imaging of vascular inflammation in abdominal aortic aneurysm in a murine model. Sci Rep. 2020 Jul 24;10(1):12410. doi: 10.1038/s41598-020-69299-y. PMID: 32709967; PMCID: PMC7381631.
  • Schrank F, Warmuth C, Görner S, Meyer T, Tzschätzsch H, Guo J, Uca YO, Elgeti T, Braun J, Sack I. Real-time MR elastography for viscoelasticity quantification in skeletal muscle during dynamic exercises. Magn Reson Med. 2020 Jul;84(1):103-114. doi: 10.1002/mrm.28095. Epub 2019 Nov 27. PMID: 31774210.
  • Schaafs LA, Schrank F, Warmuth C, Steffen IG, Braun J, Hamm B, Sack I, Elgeti T. Steady-State Multifrequency Magnetic Resonance Elastography of the Thoracic and Abdominal Human Aorta-Validation and Reference Values. Invest Radiol. 2020 Jul;55(7):451-456. doi: 10.1097/RLI.0000000000000654. PMID: 32520515.
  • Kördel M, Dehlinger A, Seim C, Vogt U, Fogelqvist E, Sellberg JA, Stiel H, Hertz HM. Laboratory water-window X-ray microscopy. Optica. 2020; 7(6): 658-674.
  • Wells J, Paysen H, Kosch O, Wiekhorst F. Heat dissipation and safety considerations during Lissajous scanning magnetic particle imaging. International Journal on Magnetic Particle Imaging 6(2), Suppl. 1, 2020, Article ID: 2009048, DOI: 10.18416/IJMPI.2020.2009048.
  • Paysen H, Kosch O, Wells J, Schaeffter T, Wiekhorst F. Characterization of noise and background components in MPI raw signals. International Journal on Magnetic Particle Imaging 6(2), Suppl. 1, 2020, Article ID: 2009028, DOI: 10.18416/IJMPI.2020.2009028.
  • Mikuda N, Schmidt-Ullrich R, Kärgel E, Golusda L, Wolf J, Höpken UE, Scheidereit C, Kühl AA, Kolesnichenko M. Deficiency in IκBα in the intestinal epithelium leads to spontaneous inflammation and mediates apoptosis in the gut. J Pathol. 2020 Jun;251(2):160-174. doi: 10.1002/path.5437. Epub 2020 May 29. PMID: 32222043.
  • Schrank F, Warmuth C, Tzschätzsch H, Kreft B, Hirsch S, Braun J, Elgeti T, Sack I. Cardiac-gated steady-state multifrequency magnetic resonance elastography of the brain: Effect of cerebral arterial pulsation on brain viscoelasticity. J Cereb Blood Flow Metab. 2020 May;40(5):991-1001. doi: 10.1177/0271678X19850936. Epub 2019 May 29. PMID: 31142226; PMCID: PMC7181097.
  • Burkhardt C, Tzschätzsch H, Schmuck R, Bahra M, Jürgensen C, Pelzer U, Hamm B, Braun J, Sack I, Marticorena Garcia SR. Ultrasound Time-Harmonic Elastography of the Pancreas: Reference Values and Clinical Feasibility. Invest Radiol. 2020 May;55(5):270-276. doi: 10.1097/RLI.0000000000000638. PMID: 31985600.
  • Kreft B, Tzschätzsch H, Schrank F, Bergs J, Streitberger KJ, Wäldchen S, Hetzer S, Braun J, Sack I. Time-Resolved Response of Cerebral Stiffness to Hypercapnia in Humans. Ultrasound Med Biol. 2020 Apr;46(4):936-943. doi: 10.1016/j.ultrasmedbio.2019.12.019. Epub 2020 Jan 28. Erratum in: Ultrasound Med Biol. 2020 Jun;46(6):1551. PMID: 32001088.
  • Miller RL, Guimond SE, Schwörer R, Zubkova OV, Tyler PC, Xu Y, Liu J, Chopra P, Boons GJ, Grabarics M, Manz C, Hofmann J, Karlsson NG, Turnbull JE, Struwe WB, Pagel K. Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides. Nat Commun. 2020 Mar 20;11(1):1481. doi: 10.1038/s41467-020-15284-y. PMID: 32198425; PMCID: PMC7083916.
  • Mura J, Schrank F, Sack I. An analytical solution to the dispersion-by-inversion problem in magnetic resonance elastography. Magn Reson Med. 2020 Jul;84(1):61-71. doi: 10.1002/mrm.28247. Epub 2020 Mar 6. PMID: 32141650.
  • Schaafs LA, Tzschätzsch H, Steffen IG, Braun J, Hamm B, Sack I, Elgeti T. Quantification of Aortic Stiffness by Ultrasound Time-Harmonic Elastography: The Effect of Intravascular Pressure on Elasticity Measures in a Porcine Model. Invest Radiol. 2020 Mar;55(3):174-180. doi: 10.1097/RLI.0000000000000618. PMID: 31895220.
  • Reiter R, Tzschätzsch H, Schwahofer F, Haas M, Bayerl C, Muche M, Klatt D, Majumdar S, Uyanik M, Hamm B, Braun J, Sack I, Asbach P. Diagnostic performance of tomoelastography of the liver and spleen for staging hepatic fibrosis. Eur Radiol. 2020 Mar;30(3):1719-1729. doi: 10.1007/s00330-019-06471-7. Epub 2019 Nov 11. PMID: 31712963; PMCID: PMC7033143.
  • Poller WC, Löwa N, Schleicher M, Münster-Wandowski A, Taupitz M, Stangl V, Ludwig A, Wiekhorst F. Initial interaction of citrate-coated iron oxide nanoparticles with the glycocalyx of THP-1 monocytes assessed by real-time magnetic particle spectroscopy and electron microscopy. Sci Rep. 2020 Feb 27;10(1):3591. doi: 10.1038/s41598-020-60162-8. PMID: 32107402; PMCID: PMC7046775.
  • Adams LC, Brangsch J, Reimann C, Kaufmann JO, Nowak K, Buchholz R, Karst U, Botnar RM, Hamm B, Makowski MR. Noninvasive imaging of vascular permeability to predict the risk of rupture in abdominal aortic aneurysms using an albumin-binding probe. Sci Rep. 2020 Feb 24;10(1):3231. doi: 10.1038/s41598-020-59842-2. Erratum in: Sci Rep. 2021 Apr 30;11(1):9675. PMID: 32094414; PMCID: PMC7039902.
  • Paysen H, Loewa N, Stach A, Wells J, Kosch O, Twamley S, Makowski MR, Schaeffter T, Ludwig A, Wiekhorst F. Cellular uptake of magnetic nanoparticles imaged and quantified by magnetic particle imaging. Sci Rep. 2020 Feb 5;10(1):1922. doi: 10.1038/s41598-020-58853-3. PMID: 32024926; PMCID: PMC7002802.
  • Becker KM, Blaszczyk E, Funk S, Nuesslein A, Schulz-Menger J, Schaeffter T, Kolbitsch C. Fast myocardial T1 mapping using cardiac motion correction. Magn Reson Med. 2020 Feb;83(2):438-451. doi: 10.1002/mrm.27935. Epub 2019 Aug 16. PMID: 31418924.
  • Everwien H, Ariza de Schellenberger A, Haep N, Tzschätzsch H, Pratschke J, Sauer IM, Braun J, Hillebrandt KH, Sack I. Magnetic resonance elastography quantification of the solid-to-fluid transition of liver tissue due to decellularization. J Mech Behav Biomed Mater. 2020 Apr;104:103640. doi: 10.1016/j.jmbbm.2020.103640. Epub 2020 Jan 14. PMID: 32174398.
  • Wang S, Millward JM, Hanke-Vela L, Malla B, Pilch K, Gil-Infante A, Waiczies S, Mueller S, Boehm-Sturm P, Guo J, Sack I, Infante-Duarte C. MR Elastography-Based Assessment of Matrix Remodeling at Lesion Sites Associated With Clinical Severity in a Model of Multiple Sclerosis. Front Neurol. 2020 Jan 13;10:1382. doi: 10.3389/fneur.2019.01382. PMID: 31998225; PMCID: PMC6970413.
  • Kreft B, Bergs J, Shahryari M, Danyel LA, Hetzer S, Braun J, Sack I, Tzschätzsch H. Cerebral Ultrasound Time-Harmonic Elastography Reveals Softening of the Human Brain Due to Dehydration. Front Physiol. 2021 Jan 11;11:616984. doi: 10.3389/fphys.2020.616984. PMID: 33505319; PMCID: PMC7830390.
  • Streitberger KJ, Lilaj L, Schrank F, Braun J, Hoffmann KT, Reiss-Zimmermann M, Käs JA, Sack I. How tissue fluidity influences brain tumor progression. Proc Natl Acad Sci U S A. 2020 Jan 7;117(1):128-134. doi: 10.1073/pnas.1913511116. Epub 2019 Dec 16. PMID: 31843897; PMCID: PMC6955323.
  • Lettow M, Grabarics M, Mucha E, Thomas DA, Polewski Ł, Freyse J, Rademann J, Meijer G, von Helden G, Pagel K. IR action spectroscopy of glycosaminoglycan oligosaccharides. Anal Bioanal Chem. 2020 Jan;412(3):533-537. doi: 10.1007/s00216-019-02327-7. Epub 2019 Dec 18. PMID: 31853603; PMCID: PMC6992547.
  •  

2019

  • Ziegler JF, Böttcher C, Letizia M, Yerinde C, Wu H, Freise I, Rodriguez-Sillke Y, Stoyanova AK, Kreis ME, Asbach P, Kunkel D, Priller J, Anagnostopoulos I, Kühl AA, Miehle K, Stumvoll M, Tran F, Fredrich B, Forster M, Franke A, Bojarski C, Glauben R, Löscher BS, Siegmund B, Weidinger C. Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn's disease. Nat Commun. 2019 Dec 10;10(1):5629. doi: 10.1038/s41467-019-13559-7. PMID: 31822667; PMCID: PMC6904732.
  • Lee CH, Vellayappan B, Taupitz M, Hamm B, Asbach P. Dynamic contrast-enhanced MR imaging of the prostate: intraindividual comparison of gadoterate meglumine and gadobutrol. Eur Radiol. 2019 Dec;29(12):6982-6990. doi: 10.1007/s00330-019-06321-6. Epub 2019 Jul 1. PMID: 31264013.
  • Shahryari M, Tzschätzsch H, Guo J, Marticorena Garcia SR, Böning G, Fehrenbach U, Stencel L, Asbach P, Hamm B, Käs JA, Braun J, Denecke T, Sack I. Tomoelastography Distinguishes Noninvasively between Benign and Malignant Liver Lesions. Cancer Res. 2019 Nov 15;79(22):5704-5710. doi: 10.1158/0008-5472.CAN-19-2150. Epub 2019 Sep 24. PMID: 31551364.
  • Schaafs LA, Tzschätzsch H, Reshetnik A, van der Giet M, Braun J, Hamm B, Sack I, Elgeti T. Ultrasound Time-Harmonic Elastography of the Aorta: Effect of Age and Hypertension on Aortic Stiffness. Invest Radiol. 2019 Nov;54(11):675-680. doi: 10.1097/RLI.0000000000000590. PMID: 31299035.
  • Kratz H, Mohtashamdolatshahi A, Eberbeck D, Kosch O, Hauptmann R, Wiekhorst F, Taupitz M, Hamm B, Schnorr J. MPI Phantom Study with A High-Performing Multicore Tracer Made by Coprecipitation. Nanomaterials (Basel). 2019 Oct 16;9(10):1466. doi: 10.3390/nano9101466. PMID: 31623127; PMCID: PMC6835925.
  • Wang S, Hesse B, Roman M, Stier D, Castillo-Michel H, Cotte M, Suuronen JP, Lagrange A, Radbruch H, Paul F, Taupitz M, Schellenberger E, Sack I, Infante-Duarte C. Increased Retention of Gadolinium in the Inflamed Brain After Repeated Administration of Gadopentetate Dimeglumine: A Proof-of-Concept Study in Mice Combining ICP-MS and Micro- and Nano-SR-XRF. Invest Radiol. 2019 Oct;54(10):617-626. doi: 10.1097/RLI.0000000000000571. PMID: 31033673.
  • Lang ST, Guo J, Bruns A, Dürr M, Braun J, Hamm B, Sack I, Marticorena Garcia SR. Multiparametric Quantitative MRI for the Detection of IgA Nephropathy Using Tomoelastography, DWI, and BOLD Imaging. Invest Radiol. 2019 Oct;54(10):669-674. doi: 10.1097/RLI.0000000000000585. PMID: 31261295.
  • Reimann C, Brangsch J, Kaufmann JO, Adams LC, Onthank DC, Thöne-Reineke C, Robinson SP, Hamm B, Botnar RM, Makowski MR. Dual-probe molecular MRI for the in vivo characterization of atherosclerosis in a mouse model: Simultaneous assessment of plaque inflammation and extracellular-matrix remodeling. Sci Rep. 2019 Sep 25;9(1):13827. doi: 10.1038/s41598-019-50100-8. PMID: 31554825; PMCID: PMC6761132.
  • Bertalan G, Boehm-Sturm P, Schreyer S, Morr AS, Steiner B, Tzschätzsch H, Braun J, Guo J, Sack I. The influence of body temperature on tissue stiffness, blood perfusion, and water diffusion in the mouse brain. Acta Biomater. 2019 Sep 15;96:412-420. doi: 10.1016/j.actbio.2019.06.034. Epub 2019 Jun 25. PMID: 31247381.
  • Grossmann M, Tzschätzsch H, Lang ST, Guo J, Bruns A, Dürr M, Hoyer BF, Grittner U, Lerchbaumer M, Nguyen Trong M, Schultz M, Hamm B, Braun J, Sack I, Marticorena Garcia SR. US Time-Harmonic Elastography for the Early Detection of Glomerulonephritis. Radiology. 2019 Sep;292(3):676-684. doi: 10.1148/radiol.2019182574. Epub 2019 Jul 9. PMID: 31287390.
  • Heucke N, Wuensch T, Mohr J, Kaffarnik M, Arsenic R, Sinn B, Müller T, Pratschke J, Stockmann M, Sack I, Tzschätzsch H. Non-invasive structure-function assessment of the liver by 2D time-harmonic elastography and the dynamic Liver MAximum capacity (LiMAx) test. J Gastroenterol Hepatol. 2019 Sep;34(9):1611-1619. doi: 10.1111/jgh.14629. Epub 2019 Mar 10. PMID: 30756433.
  • de Schellenberger AA, Tzschätzsch H, Polchlopek B, Bertalan G, Schrank F, Garczynska K, Janmey PA, Braun J, Sack I. Sensitivity of multifrequency magnetic resonance elastography and diffusion-weighted imaging to cellular and stromal integrity of liver tissue. J Biomech. 2019 May 9;88:201-208. doi: 10.1016/j.jbiomech.2019.03.037. Epub 2019 Apr 2. PMID: 30961968.
  • Sauer F , Oswald L , Ariza de Schellenberger A , Tzschätzsch H , Schrank F , Fischer T , Braun J , Mierke CT , Valiullin R , Sack I , Käs JA . Collagen networks determine viscoelastic properties of connective tissues yet do not hinder diffusion of the aqueous solvent. Soft Matter. 2019 Apr 3;15(14):3055-3064. doi: 10.1039/c8sm02264j. PMID: 30912548.
  • Brangsch J, Reimann C, Kaufmann JO, Adams LC, Onthank DC, Thöne-Reineke C, Robinson SP, Buchholz R, Karst U, Botnar RM, Hamm B, Makowski MR. Concurrent Molecular Magnetic Resonance Imaging of Inflammatory Activity and Extracellular Matrix Degradation for the Prediction of Aneurysm Rupture. Circ Cardiovasc Imaging. 2019 Mar;12(3):e008707. doi: 10.1161/CIRCIMAGING.118.008707. PMID: 30871334.