CRC 1340 - Matrix in Vision 

Meta menu:

From here, you can access the Emergencies page, Contact Us page, Accessibility Settings, Language Selection, and Search page.

  • Go to Emergencies.
  • Current language selection: EN

    Change language selection to:

  • Contact us:

    Campus Charité MitteCharitéplatz 1 (local address: Luisenstraße 13)
    10117 Berlin

    Campus Virchow-KlinikumAugustenburger Platz 1 (local address: Südring 4)
    13353 Berlin

    Campus Benjamin FranklinHindenburgdamm 30 (local address: Haus V, Eingang West)
    12203 Berlin

  • Accessibility:
    Contrast Settings Change contrast
    Font size
    Font size bigger: STRG+ Font size smaller: STRG-

    You can enlarge or reduce the browser window. Please use CTRL and + to zoom in or CTRL and - to zoom out. Press CTRL and 0 to reset your browser window to normal size.

Open Menu
Ein Forscher träufelt aus einer kleinen Pipette eine Flüssigkeit in ein Reagenzglas. Mehrere Reagenzgläser und ein Erlenmeyerkolben vorn rechts sind mit einer hellblauen, klaren Flüssigkeit gefüllt. Kopf und Schultern des Forschers sind nur unscharf im Hintergrund zu erkennen.

Collaborative Research Center 1340

Project picture CRC 1340

"Matrix in Vision" Collaborative Research Center (CRC 1340), funded by the Deutsche Forschungsgemeinschaft (DFG), aims at using inflammation as a pathologic case in point to experimentally investigate how the different ECM components might be targeted for in vivo imaging. This will be done for a variety of clinically relevant inflammatory disease entities. The experimental methods to be used include ex vivo and in vivo examinations with imaging probes, biophysical mechanical test procedures, biochemical analysis, histology, as well as molecule- and element-specific microscopy.

The CRC 1340 combines biological molecular methods in radiology with new biophysical insights into the role of mechanical tissue parameters in the development of disease, thus enabling 1) the investigation of the interaction of molecular imaging probes with the ECM; 2) the investigation of new imaging approaches using various types of magnetic nanoparticles and gadolinium-based imaging probes; and 3) multiscale quantification of mechanical structural elements of the ECM, ranging from microscopic collagen and glycosaminoglycan networks to macroscopic mechanical parameters investigated by clinical diagnostic elastography.